Showing posts with label diseases. Show all posts
Showing posts with label diseases. Show all posts

September 8 - Doctor Uses NUMB3RS to Stop an Epidemic!

 Posted on September 8, 2021


This is an update of my post published on September 8, 2010:



There once was a television show called NUMB3RS about a mathematician who used his math to help the FBI solve cases. To me, the history of the 1854 cholera epidemic in London reads a bit like a NUMB3RS episode!

Most people back in the mid-1800s thought that illness was caused by breathing “bad air” or miasma—breathing poisonous vapors of some sort. 

We know - especially now, living through the COVID-19 pandemic - that some illnesses are in fact connected to the air we breathe. But we now know that it is airborne germs (viruses, bacteria, fungi, etc.) - not "poisonous vapors" - that cause those diseases. In the mid-1800s, the germ theory wasn't yet established.


Also, some illnesses aren't transmitted through air.

When there was a deadly outbreak of cholera in London, Dr. John Snow talked to residents and created a map showing the location of the cases. With the map, he realized that the miasma theory of the cause of the disease didn't match the evidence. Using the interviews and the map, Dr. Snow was able to trace the outbreak to the public water pump on Broad Street in Soho.




Snow was most convinced that the pump was to blame when he discovered that people who lived nearby who did NOT use water from that pump also did not come down with cholera.

Snow examined a sample of the water through a microscope, and ran some chemical tests as well, and he was not able to conclusively prove its danger. However, he still used statistics and his map to convince the local council to disable the water pump by removing its handle on this date in 1854.



And the outbreak stopped.

Later, it was discovered that this public well had been dug only three feet from an old cesspit, and it was being polluted by sewage.

There is still a replica of the Broad Street 

 
Dr. Snow went on to use statistics to show that a waterworks company was using water from sewage-polluted portions of the Thames River for use in homes—and those homes suffered from more cases of cholera than other homes. Because of Dr. Snow's work, our understanding of disease prevention and public health took a giant leap.

Hooray for numbers!

Learn more...

  • Here is a virtual tour of a modern water treatment plant. And here is a longer (and I believe better) video tour.


  • Part of numbers and statistics is probability. Try using this dice-roll simulation. Roll the dice 5 time, then 50, 500, and 5000. How does the number of rolls affect the results?

Also on this date:








































July 16 - Happy Birthday, Joseph Goldberger

Posted on July 16, 2021

This is an update of my post published on July 16, 2010:



Born on this day in 1874, in Hungary, Joseph Goldberger came over to the U.S. with his parents in 1883. He became a doctor and studied diseases (which means he was an epidemiologist), and he was nominated for the Nobel Prize five times for his work on the disease called pellagra.

When Goldberger was asked to study pellagra, most doctors thought it was an infectious disease that spread from person to person. However, Goldberger thought it was related to diet. He did some careful restricted-diet experiments with volunteers—studies that spanned several years—and Goldberger was able to show that people who had diets of mostly corn and corn products were at a greatly-increased risk to get the disease.


By 1928 Goldberger was able to determine that it was a Vitamin B3 (niacin) deficiency that caused pellagra.

Unfortunately, Goldberger died the next year of cancer.

Foods high in niacin include eggs, meat, avocados, tomatoes, leafy vegetables, broccoli, carrots, nuts, legumes, and mushrooms (plus many more!).



Quick Quiz

Which of these diseases is caused by a vitamin deficiency (but of another vitamin, other than B3)?

1. rickets
2. pneumonia
3. flu
4. scurvy


ANSWERS: 
(1) Rickets is Vitamin D deficiency. 
(4) Scurvy is Vitamin C deficiency.

Find Out More

Here is a website with info about vitamins and what they do in our bodies. There are lots of other health topics to click on, too!

A simple, fun approach to vitamins is this You Tube video!